Expansion Therapeutics Developments in Controlling DM1

Expansion Therapeutics is a medical research firm that was founded by Dr. Stock Rocklage. Recently, the firm in collaboration with other research institutions took part in fighting myotonic dystrophy. This condition is also known as DM1. Other research bodies that took part in this campaign include Sanofi Ventures, Novartis Venture Fund, Kleiner Perkins, 5 AM Ventures, Alexandria Venture Investments and RA Capital Management. Expansion Therapeutics are very committed to fighting this disorder in entirety. They recently added $55.3 million to their research kitty for ensuring that the effects of this disorder are curbed at an early stage.

 

DM1 is the causative agent of a condition called muscular dystrophy. This condition is prevalent in adults. It results from overproduction of RNAs in the human body. When these chemicals are in excess, they become toxic. This toxicity leads to DM1. DM1 is a severe condition as it affects the functioning of body systems. More than one system can become affected resulting in paralysis of the entire body. It is, therefore, a serious condition that should be controlled if possible.

 

Unfortunately, DM1 is genetically transmitted. This means that an individual can inherit the disorder from relatives. The disease is more serious with the subsequent generation. This shows that there is a need to find a solution to this ailment that affects unexpecting individuals. Currently, there is no cure for DM1. However, with the ongoing researches in firms such as Expansion Therapeutics, there is hope that the disorder will be controlled. Expansion Therapeutics is currently relying on the study conducted at the laboratory of Dr. Mathew Disney as the starting point of their analysis.

 

Dr. Scott Rocklage is one of the Founding Partners of 5 AM Venture Management LLC. He has worked in this firm for numerous years. Initially, Dr. Rocklage was a managing partner of the firm. He has held other high profile positions in multiple companies. From May 2016, Dr. Rocklage has been serving as the CEO of EPIRUS Biopharmaceutical Inc. He has also been the CEO and Amersham Health during his illustrious career in the medical field.

 

To learn more, visit http://5amventures.com/team/scott-m-rocklage-phd/.

Gregory James Aziz And His Task Of Moving National Steel Car Forward

As CEO National Steel Car, Gregory James Aziz is a high-energy professional who knows what it takes to lead an organization such as this historic one. When he took on the role purchasing this railroad company in 1994, he knew that he had a challenge on his hands.

However, that did not deter him in the slightest. Gregory J Aziz was able to transform National Steel Car from a company on the decline to one that is definitely on the rise. When he took over the reins, this company only managed 3,500 cars. In just five years, he was able to grow this company to managing 12,000 railroad cars. How has he been such an effective leader? He does it by focusing on three core principles:

  • Raising The Bar.

James Aziz and his associates are always looking at ways to improve the company. They never settle for second best. One of the things that Gregory J Aziz is truly proud of will be the fact that National Steel Car does not simply rest on past achievements.

  • Exceeding Expectations.

Gregory Aziz is always looking to exceed expectations in his leadership at National Steel Car. For example, this railroad freight company is the only one in North America that is certified ISO 9001:2008, having maintained it for the past eighteen years.

  • Highest Quality.

Alone these same lines, Gregory J Aziz has always insisted on quality for all company endeavors. Indeed, their consistent efficiency has always set them apart from other railroad freight companies. For example, his company has been able to maintain the TTX SECO highest quality award on numerous occasions since 1996. Of course, one of the best things about Greg Aziz would be the fact that his commitment does not end with just his company.

 

He also extends it to Hamilton, the community in which National Steel Car is headquartered. He regularly donates two such projects as the Theater Aquarius, the Hamilton Opera, and the United Way, the Salvation Army, along with a number of other local Hamilton charities. Simply put, hard work is just a way of life for this man, both and his duties as CEO and in his community. See This Page for related information.

A Closer Look at Elysium Health

Elysium Health was founded in 2014 by Dr. Leonard Guarente, Eric Marcotulli,  and Dan Alminana. Dr. Guarente, in addition to his duties as the chief scientist of Elysium Health, is the director of the Glenn Center for Biology of Aging at MIT. During his scientific career, he conducted significant research on the molecular and genetic causes of aging.

Elysium Health’s main goal is to translate advances in science and technology into clinically validated health products that work. Right now, the company sells the supplement Basis. This supplement works to increase levels of NAD+ in our cells.

NAD+ is an essential coenzyme to many of our cellular functions, including circadian rhythms, energy creation, DNA protection, and hundreds of others. As we get older, our levels of NAD+ decline naturally. Basis supports cellular functions and, as a result, our cellular well-being by increasing levels of NAD+.

Basis is clinically-proven to increase levels of NAD+ by an average of 40 percent in humans. Elysium Health put the supplement through a clinical trial in 2016 that showed these results. The science journal npj: Aging and Mechanisms of Disease published these results.

Basis is designed for long-term use and is available for purchase on Elysium Health’s website. Since each jar of Basis contains about a month’s worth of supplement, there is a variety of subscriptions available to purchase. An ongoing subscription costs $50 per month. The most popular deal is the six-month subscription for $270, which ends up as $45 per month. An individual jar of the supplement is also available for purchase for $60.

Elysium Health is also developing new products that focus on the microbiome, cognitive health, skin health, muscle function, and circadian rhythms. These products are in various stages of pre-clinical and clinical trials.

More information on Elysium Health, the company’s team of scientists, and the science behind Basis can be found on Elysium’s website

https://www.crunchbase.com/organization/elysium-health#/entity

Have You Heard Of A Businessman And Leader Named Gregory Aziz?

Have you ever heard the name Gregory James Aziz? Do you know what he is known for? He has many accomplishments but the greatest of them is his purchase of his company, National Steel Car, in 1994. This is ultimately where Gregory J Aziz’s success and reputation started becoming known. Greg Aziz was the chairman and the chief executive officer of National Steel Car and still is today. When he purchased the company in 1994, it was very small employing only six hundred people.

 

This was one of the major changes that came about with Greg’s overseeing of the company. By 1999, the employee number stood at 3,000. National Steel Car was becoming something few people believed it could be. From producing only 3,500 cars a year when purchased, it was able to produce 12,500 by the year 1999. Greg Aziz was happy but he didn’t stop there. He continued to invest himself into his company ensuring it continued to grow and expand. Greg’s leadership and hard work was recognized by several people including the people he worked with.

 

When Greg was a child, he was a big dreamer and this continued all throughout high school. He attended Ridley College where he studied hard and learned a lot about himself in the process. He decided to major in economics. He applied to the University of Western Ontario and he was accepted. It was here he was able to major in economics and graduated from the university with a degree. Greg went on from here to partner with his family in their wholesale food company, Affiliated Foods. It was with him they were able to achieve a greater level of success and began being able to distribute food to other countries. This included parts of the United States. It was after this endeavor, Greg moved to New York and landed a job in banking with his strong economic background. Shortly after, he purchased National Steel Car and the rest is history. See This Article for more information.

 

1Greg has a wife whose name is Irene and he also has a daughter named Karina and a daughter named Natalia. They each have been by his side through the years as he grew as a person and as a businessman. Greg and his family also sponsor Canada’s Royal Agricultural Fair every year. They also recently have begun to sponsor the Angelstone Tournament as they are all four an avid lover of horses.

 

Learn More: https://www.crunchbase.com/person/gregory-aziz